Successful treatment of Oral Lichen Planus (OLP) with 0.1% topical Tacrolimus in a patient with impaired liver enzymes: A Case report
نویسندگان
چکیده
Department of oral medicine and radiology, Seema dental college and hospital, Rishekesh , Uttarkhand, India. Department of oral medicine and radiology, I.T.S. Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India Department of oral pathology, Seema dental college and hospital, Rishekesh , Uttarkhand, India Department of oral medicine and radiology, Maharana Pratap Dental College, Gwalior , Madhy Pradesh, India. Abstract In the present case report, a case of a patient with blisters in oral cavity which indicate erosive Oral Lichen Planus ( OLP) lesions associated with elevated serum SGOT, SGPT levels along positive Tri Dot for Hepatitis C Virus is reported. Outcome of the present case report suggests that extensive clinical, laboratory and microscopic evaluation is necessary to identify the probable etiology of the condition and to choose the most appropriate treatment regimen.
منابع مشابه
The Effect of Pimecrolimus Cream 1% Compared with Triamcinolone Acetonide Paste in Treatment of Atrophic-Erosive Oral Lichen Planus
Introduction: Oral lichen planus (OLP) is a common chronic mucocutaneous disease. Patients with atrophic and erosive types of OLP often have symptoms of soreness, and require proper treatment. The main treatment for OLP has been the administration of topical or systemic corticosteroids. The objective of this study was to compare the efficacy of adcortyl cream (triamcinolone acetonide in orabase...
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Introduction: Oral lichen planus (OLP) is an autoimmune disease with uncertain etiopathogenecity and no definitive treatment. Considering the recurrent nature of OLP, finding an adjunctive treatment to minimize the risk of chronicity and recurrence of OLP and to decrease the adverse effects of corticosteroids can be promising. This study aimed to assess the efficacy of a mixture of hyaluronic a...
متن کاملA randomized triple-blind clinical trial to compare the effectiveness of topical triamcinolone acetonate (0.1%), clobetasol propionate (0.05%), and tacrolimus orabase (0.03%) in the management of oral lichen planus
BACKGROUND Oral lichen planus (OLP) is believed to result from an abnormal T-cell mediated immune response. The most useful agent in the treatment is corticosteroids. The present study will be aimed at evaluation of therapeutic efficiency of two corticosteroids triamcinolone acetonate (0.1%) and clobetasol propionate with tacrolimus orabase (0.03%), an immunomodulator in the management of OLP. ...
متن کاملManagement of Oral Lichen Planus
Oral lichen planus (OLP) is a chronic inflammatory disease characterized by relapses and remissions. There is currently no cure for OLP. Treatment is aimed primarily at reducing the length and severity of symptomatic outbreaks. Topical steroids are the first-choice agent for the treatment of symptomatic, active OLP. Other topical agents that have been used in cases resistant to topical steroids...
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Hepatitis C virus (HCV) infection is frequently associated with various extrahepatic manifestations, such as autoimmune features and immune complex deposit diseases. Oral lichen planus (OLP) is one such extrahepatic manifestation of HCV infection. Recently, direct-acting antivirals (DAA) have proved to be highly effective and safe for the eradication of HCV. Herein, we report a case of OLP acco...
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